Transplantation of bone marrow for leukemia patients
Sunday, December 27, 2009 by Admin
For the treatment of acute leukemia is to destroy cancer cells until they are exhausted. The implementation in stages and consists of several cycles. Is the induction stage (early), consolidation and maintenance. Induction phase is to destroy cancer cells gradually. to eliminate remaining cancer cells of the consolidation phase to achieve a full recovery. Phase maintenance is useful to keep it once more. The usual treatment with chemotherapy, radiotherapy and bone marrow transplantation and leukemia tulang.Untuk acute treatment with the aim to destroy the cancer cells until they are exhausted. The implementation in stages and consists of several cycles. Is the induction stage (early), consolidation and maintenance. Induction phase is to destroy cancer cells gradually. to eliminate remaining cancer cells of the consolidation phase to achieve a full recovery. Phase maintenance is useful to keep it once more. The usual treatment with chemotherapy, radiotherapy and bone marrow transplantation.
Bone marrow is soft tissue in the inner cavity of the bone, found that's where most of the production of new blood cells. There are two types of bone marrow: red marrow (also known as myeloid tissue) and yellow bone marrow. Red blood cells, platelets and most of the white blood cells of red bone marrow. Yellow bone marrow produces white blood cells and the color of fat cells that contain many causes. Both types of bone marrow contains many blood vessels and capillaries.
Bone marrow transplantation is a procedure that will replace the damaged bone marrow with healthy bone marrow. Bone marrow damage can be caused by high doses of chemotherapy or radiation therapy. In addition, bone marrow transplantation is also useful to replace blood cells destroyed by cancer. The bone marrow transplant, the patient's own bone marrow is still healthy. This is called autologous bone marrow transplantation. Bone marrow transplantation can also be obtained by others. If obtained from an identical twin called syngeneic transplantation. Meanwhile, if obtained from non-identical twins, for example, the siblings, named after allogeneic transplantation. Currently, allogeneic bone marrow transplants are most often done.
Why do bone marrow transplantation in the treatment of leukemia needed? The main reason he did was for these patients, treatment with high-dose chemotherapy or radiotherapy can be given. to understand why bone marrow transplant is needed to understand how to work chemotherapy and radiotherapy. Chemotherapy and radiation therapy generally affect cells that divide quickly. They are used because cancer cells divide more rapidly than healthy cells. However, since bone marrow cells also divide frequently enough, the treatment with high doses damage the cells of the bone marrow. Without healthy bone marrow, the patient can not generate blood cells are needed. Healthy bone marrow transplantation, the ability of blood cells, patients have to produce to restore.
Side effects of bone marrow transplantation remain, namely the possibility of infection and bleeding are possible, as high doses of cancer treatment. This may be an indication of antibiotics or blood transfusions to prevent anemia can be overcome. If successful bone marrow transplant, the patient can recover by 70-80%, but still possible to relapse again. If you do not, bone marrow transplants, only 40-50% cure rate.
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